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Frontline Gastroenterol 3:180-186 doi:10.1136/flgastro-2011-100097
  • Reviews

Gene–environment interactions in inflammatory bowel disease: microbiota and genes

  1. Marian C Aldhous
  1. Correspondence to Dr Marian C Aldhous, MRC Centre for Reproductive Health, The Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK; maldhous{at}ed.ac.uk
  • Received 14 December 2011
  • Accepted 10 April 2012

Abstract

A recent research workshop gave an update on the genetics of the inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis. This mini-review summarises the updates of the gene–environmental interactions, especially those outlining the contribution of the gut microbiota to the pathogenesis of IBD.

Footnotes

  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.