TY - JOUR T1 - A practical guide to thiopurine prescribing and monitoring in IBD JF - Frontline Gastroenterology JO - Frontline Gastroenterol DO - 10.1136/flgastro-2016-100738 SP - flgastro-2016-100738 AU - Ben Warner AU - Emma Johnston AU - Monica Arenas-Hernandez AU - Anthony Marinaki AU - Peter Irving AU - Jeremy Sanderson Y1 - 2016/08/29 UR - http://fg.bmj.com/content/early/2016/08/29/flgastro-2016-100738.abstract N2 - Thiopurines are often the mainstay of treatment for many patients with inflammatory bowel disease. As such, a general understanding of the evidence behind their use and of their metabolism is extremely useful in clinical practice. This review gives a practical overview of thiopurine metabolism, the importance of thiopurine S-methyltransferase testing prior to the start of therapy and the monitoring of thioguanine nucleotide levels while on treatment, guiding a personalised approach to optimising thiopurine therapy. ER -