Table 1

Cotton grades of difficulty of endoscopic retrograde cholangiopancreatography (ERCP) procedures7

GradeProcedure
1Deep cannulation of duct of interest, main papilla or sampling
Biliary stent removal or exchange
2Biliary stone extraction <10 mm
Treatment of biliary leaks
Treatment of extrahepatic strictures (benign or malignant)
Placement of prophylactic pancreatic stents
3Biliary stone extraction >10 mm
Minor papilla cannulation in divisum and therapy
Removal of internally migrated biliary stents
Intraductal imaging, biopsy or fine-needle aspiration
Management of acute or recurrent pancreatitis
Treatment of pancreatic strictures
Removal of pancreatic stones that are mobile and <5 mm
Treatment of hilar tumours
Treatment of benign biliary strictures, hilum and above
Management of sphincter of Oddi dysfunction (with or without mannometry)
4Removal of internally migrated pancreatic stents
Intraductal image-guided therapy (eg, photodynamic therapy)
Removal of intrahepatic stones
Pseudocyst drainage or necrosectomy
Ampullectomy
ERCP after a Whipple procedure or Roux-en-Y bariatric surgery
  • One grade should be added (for a maximum grade of 4) for procedures performed after normal working hours, children under 3 years of age, in post-Billroth II gastrectomy patients, or for procedures that have previously failed.