Sensitivity and specificity at different cut-off ranges to distinguish IBS from IBD and IBD in remission compared with active disease
| Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | |
|---|---|---|---|---|
| IBS vs IBD at FC 50 μg/g | 87.5 | 77.7 | 79.2 | 86.5 |
| IBS vs IBD at FC 100 μg/g | 97.2 | 76.3 | 75.3 | 97.4 |
| IBD remission vs active at FC 50 μg/g | 55.2 | 98.9 | 97.0 | 77.4 |
| IBD remission vs active at FC 100 μg/g | 72.4 | 95.6 | 91.3 | 84.3 |
| IBD remission vs active at FC 250 μg/g | 89.7 | 75.6 | 70.3 | 91.9 |
FC, faecal calprotectin; IBD, inflammatory bowel disease; IBS, irritable bowel syndrome; NPV, negative predictive value; PPV, positive predictive value.