Cut-offs for non-severe/severe disease | Approximate 28-day survival if severe | ||||||||
---|---|---|---|---|---|---|---|---|---|
Score | Formula | Low | High | Without treatment | With treatment | ||||
DF | 4.5 (PT-control PT)+(bilirubin/17) | <32 | 32+ | 65% | 80% | ||||
GAHS | 1 | 2 | 3 | <9 | 9+ | 50% | 78% | ||
Age | <50 | 50+ | |||||||
WCC | <1.5 | 1.5+ | |||||||
Urea | <5 | 5+ | |||||||
INR | <1.5 | 1.5–2 | 2+ | ||||||
Bilirubin | <125 | 125–250 | >250 | ||||||
ABIC | (age years×0.01)+(bilirubin mg/dL×0.8)+(creatinine mg/dL×0.3)+(INR×0.8) | <6.71 | 6.71–8.9 | >8.9 | NA | NA (6 months survival 0%) |
For GAHS, each variable scores a defined number of points which add up to the final score.
ABIC, Age, Bilirubin INR and Creatinine; GAHS, Glasgow Alcoholic Hepatitis Score; PT, prothrombin time.