Baseline characteristics by BMD
| Normal BMD (n=43) | Low BMD (n=89) | p Value | |
|---|---|---|---|
| Gender | |||
| Women | 20 (46.5) | 36 (40.4) | 0.317 (Fisher's exact) |
| Men | 23 (53.5) | 53 (59.6) | |
| Age (SD) | 56.4 (9.5) | 60.7 (9.9) | 0.02 (unpaired t test) |
| BMI (SD) | 29.3 (6.0) | 27.9 (5.8) | 0.07 (unpaired t test) |
| Aetiology (%) | |||
| AIH | 0 (0) | 1 (1.1) | 0.35 (χ2) |
| AIH/PBC | 0 (0) | 1 (1.1) | |
| ALC | 20 (46.5) | 52 (58.4) | |
| ALC/NASH | 1 (2.3) | 0 (0) | |
| CRY | 0 (0) | 2 (2.2) | |
| HBV | 2 (4.7) | 4 (4.5) | |
| HCV | 14 (32.6) | 17 (19.1) | |
| NASH | 5 (11.6) | 6 (6.7) | |
| PBC | 1 (2.3) | 6 (6.7) | |
| Child–Pugh Score (%) | |||
| A | 39 (92.9) | 81 (94.2) | 0.82 (χ2) |
| B | 3 (7.1) | 4 (4.7) | |
| C | 0 (0) | 1 (1.2) | |
| Total vitamin D serum level | 58.6 (29.2) | 58.9 (35.2) | 0.96 (unpaired t test) |
| Positive smoking history (%) | 18 (41.9) | 45 (50.6) | 0.46 (Fisher's exact) |
| Previous corticosteroid use (%) | 0 (0) | 3 (3.4) | 0.55 (Fisher's exact) |
| History of rheumatoid arthritis (%) | 0 (0) | 1 (1.1) | 1.00 (Fisher's exact) |
| Menopause (n=56) (%) | 11 (57.9) | 33 (89.2) | 0.01 (Fisher's exact) |
AIH, autoimmune hepatitis; ALC, alcohol; BMD, bone mineral density; BMI, body mass index; CRY, cryptogenic; HBV, hepatitis B virus; HCV, hepatitis C virus; NASH, non-alcoholic steatohepatitis; PBC, primary biliary cirrhosis.