Table 2

Antidrug antibody assay comparative studies

DrugComparisonPearson r correlationSpearman r correlationReference
InfliximabSanquin RIA–Leuven ELISA0.9535
Sanquin RIA–Theradiag ELISA0.99
Leuven ELISA–Theradiag ELISA0.97
InfliximabBiomonitor RIA–Prometheus ELISA0.820.6436
Biomonitor RIA–Prometheus HMSA0.770.81
Biomonitor RIA–RGA0.800.67
RGA–Prometheus ELISA0.960.78
RGA–Prometheus HMSA0.780.58
Prometheus ELISA–Prometheus HMSA0.810.54
InfliximabELISA–RIA0.7337
ELISA–RGA0.93
ELISA–EIA0.89
RIA–RGA0.75
RIA–EIA0.71
RGA–EIA0.93
InfliximabPromonitor ELISA–Sanquin RIA0.97338
AdalimumabPromonitor ELISA–Sanquin RIA0.99638
  • EIA, enzyme immunoassay; HMSA, homogenous mobility shift assay; RGA, reporter gene assay; RIA, radioimmunoassay.