Table 1

Demographic and clinicopathological characteristics of patients

South Asian (n=90)White (n=79)
Mean/MedianRangeMean/MedianRangep Value
Age (years)4424–785223–741.2×10–5
Sex (%male)73%61%0.08
Diabetes (%)42%37%0.52
BMI (kg/m2)28.619–4232.823–524.0×10–8
Liver histology
Total NAS31–631–60.47
Lobular inflammation10–210–20.01
Hepatocyte ballooning10–210–20.52
Fibrosis (Kleiner)10–410–40.60
Fibrosis stage (n)
Blood results
AST (U/l)4710–1404816–1330.75
ALT (U/l)7613–2626912–2880.37
Platelets x109/mL23762–44921940–5320.11
Albumin (g/L)4628–534533–520.04
Non-invasive liver tests
NAFLD fibrosis score−2.34−5.8–3.4−1.31−6.1–3.04.0×10–4
AST/ALT ratio0.700.3–2.00.770.3–1.70.13
  • Characteristics are summarised as mean for continuous data (age, BMI, blood results, NAFLD fibrosis score, APRI, AST/ALT and Fib-4) and as median for categorical data (histology and BARD score). Two-tailed p values compare South Asian and white patients using Student’s t-test for continuous and the Mann-Whitney test for categorical data. Proportions of patients who are male and who have diabetes are compared using the χ2 test.

  • ALT, alanine aminotransferase; APRI, aspartate transaminase (AST) to platelet ratio index; AST, aspartate aminotransferase; BMI, body mass index; NAFLD, non-alcoholic fatty liver disease; NAS, NAFLD activity score.