Table 1

Case series of patients with symptoms compatible with cyclic vomiting syndrome

Sex	Age at diagnosis (years)	History of migraine	Family history of migraine	Cannabis use	Dose of amitriptyline (mg)	Dose titrated	Remission	Duration of follow- up (years)
Female	22	Yes	No	No	10	No	DNA	DNA
Female	22	No	No	No	25	No	Yes	3
Male	24	No	No	No	10	Up to 35 mg	Yes	2
Female	19	No	No	Yes	10	Up to 25 mg	Yes	1
Male	25	No	No	Yes	10	Up to 45 mg	Improved, one further episode	4
Male	44	No	No	Yes	10	Up to 140 mg	Yes	5
Female	22	No	Yes	Yes	25	Up to 50 mg	No, continued cannabis use	1
Male	22	No	Yes	No	25	No	Yes	1
Female	30	No	No	No	25	Up to 50 mg	Improved, five further episodes	1
Female	26	No	Yes	No	25	No	DNA	DNA
Female	22	No	No	No	10	Up to 20 mg, but reduced due to lethargy	No	2
Female	28	No	No	No	10	Up to 25 mg	No	1
Female	22	No	No	Yes	N/A	N/A	DNA	DNA
Female	75	No	No	No	25	No	Yes	3
Female	55	No	No	No	N/A	N/A	Yes, without treatment	DNA
Female	26	No	Yes	No	N/A	N/A	Yes, without treatment	1
Female	22	No	Yes	No	25	Up to 75 mg	DNA	1