Table 3

Diagnostic agreement/disagreement for the various aetiologies encountered with clinical opinion at clinical review as gold standard

Diagnostic agreementDiagnostic disagreement
n26657
PBC172
AIH414
HCV460
HBV80
HFE141
Wilson’s disease00
A1AT04
NAFLD, no fibrosis9016
NAFLD with fibrosis103
ARLD, no fibrosis204
ARLD with fibrosis120
Isolated elevated ALP64
Gilbert’s syndrome00
DILI110
Unclear289
  • A1AT, alpha 1 antitrypsin; AIH, autoimmune hepatitis; ALP, alkaline phosphtase; ARLD, alcohol-related liver disease; DILI, drug-induced liver injury; HBV, hepatitis B virus infection; HCV, hepatitis C virus infection; HFE, hereditary haemochromatosis; NAFLD, non-alcoholic fatty liver disease; PBC, primary biliary cholangitis.