User profiles for "author:Daniel R Gaya"

Professor Daniel R Gaya

Consultant Gastroenterologist, Glasgow Royal Infirmary, Glasgow, UK
Verified email at ggc.scot.nhs.uk
Cited by 7436

British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults

CA Lamb, NA Kennedy, T Raine, PA Hendy, PJ Smith… - Gut, 2019 - gut.bmj.com
Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease.
Both represent chronic inflammation of the gastrointestinal tract, which displays …

New genes in inflammatory bowel disease: lessons for complex diseases?

DR Gaya, RK Russell, ER Nimmo, J Satsangi - The Lancet, 2006 - thelancet.com
The chronic inflammatory bowel diseases Crohn's disease and ulcerative colitis are
common causes of gastrointestinal disease in northern Europe, affecting as many as one in …

[HTML][HTML] SARS-CoV-2 vaccination for patients with inflammatory bowel disease: a British Society of Gastroenterology Inflammatory Bowel Disease section and IBD …

JL Alexander, GW Moran, DR Gaya, T Raine… - The Lancet …, 2021 - thelancet.com
SARS-CoV-2 has caused a global health crisis and mass vaccination programmes provide
the best opportunity for controlling transmission and protecting populations. Despite the …

Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study

NA Kennedy, GA Heap, HD Green… - The lancet …, 2019 - thelancet.com
Background Anti-TNF drugs are effective treatments for the management of Crohn's disease
but treatment failure is common. We aimed to identify clinical and pharmacokinetic factors …

[HTML][HTML] HLA-DQA1* 05 carriage associated with development of anti-drug antibodies to infliximab and adalimumab in patients with Crohn's disease

A Sazonovs, NA Kennedy, L Moutsianas, GA Heap… - Gastroenterology, 2020 - Elsevier
Background & Aims Anti–tumor necrosis factor (anti-TNF) therapies are the most widely
used biologic drugs for treating immune-mediated diseases, but repeated administration can …

British Society of Gastroenterology guidance for management of inflammatory bowel disease during the COVID-19 pandemic

NA Kennedy, GR Jones, CA Lamb, R Appleby, I Arnott… - Gut, 2020 - gut.bmj.com
The COVID-19 pandemic is putting unprecedented pressures on healthcare systems
globally. Early insights have been made possible by rapid sharing of data from China and …

[HTML][HTML] Treatment of active Crohn's disease with an ordinary food-based diet that replicates exclusive enteral nutrition

V Svolos, R Hansen, B Nichols, C Quince, UZ Ijaz… - Gastroenterology, 2019 - Elsevier
Background & Aims Exclusive enteral nutrition (EEN) is the only established dietary
treatment for Crohn's disease (CD), but its acceptability is limited. There is a need for novel …

HLA-DQA1–HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants

GA Heap, MN Weedon, CM Bewshea, A Singh… - Nature …, 2014 - nature.com
Pancreatitis occurs in approximately 4% of patients treated with the thiopurines azathioprine
or mercaptopurine. Its development is unpredictable and almost always leads to drug …

Multicentre comparison of the Glasgow Blatchford and Rockall scores in the prediction of clinical end‐points after upper gastrointestinal haemorrhage

AJ Stanley, HR Dalton, O Blatchford… - Alimentary …, 2011 - Wiley Online Library
Aliment Pharmacol Ther 2011; 34: 470–475 Summary Background The Glasgow Blatchford
Score (GBS) is increasingly being used to predict intervention and outcome following upper …

Treat to target versus standard of care for patients with Crohn's disease treated with ustekinumab (STARDUST): an open-label, multicentre, randomised phase 3b trial

S Danese, S Vermeire, G d'Haens, J Panés… - The Lancet …, 2022 - thelancet.com
Background A treat-to-target strategy, in which strictly defined treatment targets facilitate
decision making in clinical practice, is advocated as an optimised management approach for …