Non-alcoholic fatty liver disease: a practical approach to diagnosis and staging
Non-alcoholic fatty liver disease (NAFLD) is now the commonest cause of abnormal liver
function tests (LFTs) in the UK with approximately a third of the population being affected …
function tests (LFTs) in the UK with approximately a third of the population being affected …
Primary sclerosing cholangitis
Primary sclerosing cholangitis is a rare, chronic cholestatic liver disease characterised by
intrahepatic or extrahepatic stricturing, or both, with bile duct fibrosis. Inflammation and …
intrahepatic or extrahepatic stricturing, or both, with bile duct fibrosis. Inflammation and …
[HTML][HTML] Colorectal cancer in inflammatory bowel disease: what is the real magnitude of the risk?
The association between inflammatory bowel disease (IBD) and colorectal cancer (CRC)
has been recognised since 1925 and still accounts for 10%-15% of deaths in IBD. IBD …
has been recognised since 1925 and still accounts for 10%-15% of deaths in IBD. IBD …
The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment and management guidelines
GM Hirschfield, JK Dyson, GJM Alexander… - Gut, 2018 - gut.bmj.com
Primary biliary cholangitis (formerly known as primary biliary cirrhosis, PBC) is an
autoimmune liver disease in which a cycle of immune mediated biliary epithelial cell injury …
autoimmune liver disease in which a cycle of immune mediated biliary epithelial cell injury …
British Society of Gastroenterology and UK-PSC guidelines for the diagnosis and management of primary sclerosing cholangitis
MH Chapman, D Thorburn, GM Hirschfield… - Gut, 2019 - gut.bmj.com
These guidelines on the management of primary sclerosing cholangitis (PSC) were
commissioned by the British Society of Gastroenterology liver section. The guideline writing …
commissioned by the British Society of Gastroenterology liver section. The guideline writing …
Novel therapeutic targets in primary biliary cirrhosis
Primary biliary cirrhosis (PBC) is a chronic immune-mediated liver disease characterized by
progressive cholestasis, biliary fibrosis and eventually cirrhosis. It results in characteristic …
progressive cholestasis, biliary fibrosis and eventually cirrhosis. It results in characteristic …
Republished: non-alcoholic fatty liver disease: a practical approach to treatment
Non-alcoholic fatty liver disease (NAFLD) affects up to a third of the population in many
developed countries. Between 10% and 30% of patients with NAFLD have non-alcoholic …
developed countries. Between 10% and 30% of patients with NAFLD have non-alcoholic …
The new epidemiology of primary biliary cirrhosis
Primary biliary cirrhosis (PBC) is an autoimmune cholestatic liver disease. Susceptibility to
PBC probably arises from a combination of genetic and environmental factors. The …
PBC probably arises from a combination of genetic and environmental factors. The …
[HTML][HTML] Liver toxicity associated with sofosbuvir, an NS5A inhibitor and ribavirin use
Hepatitis C virus (HCV) infection is a major cause of end-stage liver disease and
hepatocellular carcinoma. There have been rapid advances in HCV treatment with the …
hepatocellular carcinoma. There have been rapid advances in HCV treatment with the …
Long-term fenofibrate treatment in primary biliary cholangitis improves biochemistry but not the UK-PBC risk score
Background Fenofibrate (FF) has been suggested as a second-line agent in primary biliary
cholangitis (PBC) patients who do not achieve adequate biochemical response to …
cholangitis (PBC) patients who do not achieve adequate biochemical response to …