Secondary neoplasms of the breast: a survey of the 20th Century

SN Georgiannos, J Chin Aleong, AW Goode… - Cancer, 2001 - Wiley Online Library
BACKGROUND A 90‐year archive of surgical and postmortem material was reviewed to
establish the incidence, presentation, and pathology of tumors secondary to the breast …

Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma

A Ene–Obong, AJ Clear, J Watt, J Wang, R Fatah… - Gastroenterology, 2013 - Elsevier
Background & Aims Pancreatic ductal adenocarcinoma (PDAC) is characterized by a
prominent desmoplastic microenvironment that contains many different immune cells …

Clonality assessment and clonal ordering of individual neoplastic crypts shows polyclonality of colorectal adenomas

C Thirlwell, OCC Will, E Domingo, TA Graham… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: According to the somatic mutation theory, monoclonal colorectal
lesions arise from sequential mutations in the progeny of a single stem cell. However …

Small-molecule Wnt inhibitors are a potential novel therapy for intestinal fibrosis in Crohns disease

A Lewis, S Sánchez, G Berti, B Pan-Castillo… - Clinical …, 2022 - portlandpress.com
Intestinal fibrosis and stricture formation is an aggressive complication of Crohns disease
(CD), linked to increased morbidity and costs. The present study investigates the …

Changes in neuromuscular structure and functions of human colon during ageing are region-dependent

J Broad, VWS Kung, A Palmer, S Elahi, A Karami… - Gut, 2019 - gut.bmj.com
Objective To determine if human colonic neuromuscular functions decline with increasing
age. Design Looking for non-specific changes in neuromuscular function, a standard burst of …

Non-invasive markers of liver fibrosis in fatty liver disease are unreliable in people of South Asian descent

S De Silva, W Li, P Kemos, JH Brindley, J Mecci… - Frontline …, 2018 - fg.bmj.com
Objective Liver biopsy is the most accurate method for determining stage and grade of injury
in non-alcoholic fatty liver disease (NAFLD). Given risks and limitations of biopsy, non …

[HTML][HTML] Expression of p16 within myenteric neurons of the aged colon: a potential marker of declining function

A Palmer, S Epton, E Crawley, M Straface… - Frontiers in …, 2021 - frontiersin.org
Human colonic neuromuscular functions decline among the elderly. The aim was to explore
the involvement of senescence. A preliminary PCR study looked for age-dependent …

Solid pseudopapillary tumour of the pancreas: clinicopathological analysis

S McCluney, N Wijesuriya… - ANZ journal of …, 2018 - Wiley Online Library
Background We report on our experience of the surgical management and outcomes of 11
patients with solid pseudopapillary tumour of the pancreas (SPT). We sought to correlate the …

Clinical value of immunohistochemically detected lymphovascular space invasion in early stage cervical carcinoma

CS Lim, F Alexander-Sefre, M Allam, N Singh… - Annals of surgical …, 2008 - Springer
Background This study investigates the clinical significance of lymphovascular space
invasion (LVSI) as detected by hematoxylin and eosin (LVSI-H&E) and …

Expression of polymeric immunoglobulin receptor and stromal activity in pancreatic ductal adenocarcinoma

P Arumugam, S Bhattacharya, J Chin-Aleong… - Pancreatology, 2017 - Elsevier
Background/objectives Polymeric immunoglobulin receptor (pIgR) traffics Immunoglobulins
(IgA and IgM) through epithelial cells in normal mucosae but neither are expressed in the …