There is increasing and consistent evidence that cancer-associated inflammation is a key
determinant of outcome in patients with cancer. Various markers of inflammation have been …

Background Operative injury to the body from all procedures causes a stereotypical cascade
of neuroendocrine, cytokine, myeloid, and acute phase responses. This response has been …

Introduction Cancer remains a leading cause of death worldwide. While a curative intent is
the aim of any surgical treatment many patients either present with or go onto develop …

The major complication in the performance of hepatic rectional surgery is hemorrhage. This
report describes a novel technique to achieve hepatic parenchymal division. Preliminary use …

INTRODUCTION: Components of the systemic inflammatory response, combined to form
inflammation-based prognostic scores (modified Glasgow Prognostic Score (mGPS) …

The metastatic process of colorectal cancer (CRC) is not fully understood and effective
therapies are lacking. We show that activation of NOTCH1 signaling in the murine intestinal …

Cancer remains a leading causes of death worldwide and an elevated systemic
inflammatory response (SIR) is associated with reduced survival in patients with operable …

Background Infective complications particularly in the form of surgical site infections
including anastomotic leak represent a serious morbidity after colorectal cancer surgery …

Objective: This study aims to examine the clinical utility of the combination of TNM stage and
modified Glasgow Prognostic Score (mGPS) in patients undergoing potentially curative …

Nuclear factor-κB (NF-κB) has been widely implicated in the development and progression
of cancer. In colorectal cancer (CRC), NF-κB has a key role in cancer-related processes …