Footnotes

• Contributors Study concept and design: CS. Acquisition of data: CS and LBR. Analysis and interpretation of data: all authors. Drafting of the manuscript: CS. Critical revision of the manuscript for important intellectual content: all authors. Final approval: all authors.

• Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

• Competing interests CS speaker and advisory board member for MSD and Janssen-Cilag. LBR speaker for Takeda.

• Provenance and peer review Not commissioned; internally peer reviewed.