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How to manage alcohol-related liver disease: a case-based review
Alcohol related liver disease is a major cause of morbidity and mortality. Management can be challenging particularly in the later stages. In this issue James Maurice and colleagues take us through the management of a case. The paper - which summarises the evidence and discusses pratical management – takes the reader from risk stratification and fibrosis assessment in the community through to managing decompensated disease, escalation to critical care and assessment for liver transplantation. The authors expand on areas of controversy including the indications for liver transplantation and future research priorities. Multidisciplinary input is essential at all stages. In conjunction with this excellent review the authors emphasise continued public health efforts are required to implement effective policies to reduce alcohol consumption and prevent disease. (See page 435)
Hepatitis C: recent advances and practical management
Hepatitis C virus (HCV) remains a leading cause of morbidity and premature death worldwide. Injecting drug use is the most important risk factor in the UK, more prevalent in high risk populations, although many are unaware they are infected. In this issue Rebecca O’Kane and colleagues discuss recent advances and practical management. This includes sections on detection, disease assessment and management. There is a useful table on the interpretation of screening tests. Short courses of oral direct acting antivirals achieve cure in>90% of people regardless of genotype and stage of liver disease (table 3). …