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Sister Mary Joseph’s nodule revealing cholangiocarcinoma
  1. Wala Ben Kridis,
  2. Tahia Boudawara,
  3. Afef Khanfir
  1. Habib Bourguiba Hospital, University of Sfax, Sfax, Tunisia
  1. Correspondence to Dr Wala Ben Kridis, Habib Bourguiba Hospital, Sfax 3029, Sfax, Tunisia; walabenkridis{at}

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A 66-year-old diabetic woman was admitted for an abdominal nodule that had been evolving for 6 months. Clinical examination found an isolated umbilical nodule of 3.5 cm without any other symptoms or signs (figure 1A). Abdominal CT showed a left hypodense hepatic nodule. Liver function tests were normal. The plasma level of CA-19-9 was elevated at 13150 IU/mL. Abdominal MRI revealed a left intrahepatic mass measuring 49×58 mm (figure 2).

Figure 1

(A) Inflammatory umbilical nodule, (B) partial response after systemic …

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  • Contributors WBK idea writing, TB revision, AK revision.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.