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The September 2023 Frontline Gastroenterology Twitter Debate (#FGDebate) focused on the safety of a no-biopsy approach to diagnosing coeliac disease (CD) for those with elevated transglutaminase IgA antibody titres (TTG-IgA). This was based on a paper published in Frontline Gastroenterology in August 2022 by Hoyle et al.1 Box 1 summarises out quick facts that arose from the debate and box 2 summarises key points from the British Society of Gastroenterology (BSG) guidance which were explored in the debate.
Coeliac disease biopsy quick facts
A no-biopsy approach allows for CD to be diagnosed in patients using serology only.
There is growing UK data that a TTG-IgA level greater than 10x the upper limit of normal can be used in patients …
Footnotes
X @sheiybani
Contributors GM wrote the main draft of the manuscript. SAR, DSS and PMG reviewed and edited the manuscript. All authors approved the final version of the manuscript.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests GM is a trainee associate editor for Frontline Gastroenterology.
Provenance and peer review Not commissioned; internally peer reviewed.
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