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We read with interest the article on extrahepatic manifestations of hepatitis C virus by Samuel and Rees.1 We report a dermatological manifestation of hepatitis C, which the authors have not mentioned.
A 38-year-old man with hepatitis C was admitted with upper gastrointestinal bleed. He was found to have oesophageal varices that were banded. He developed a tender purpuric rash with ulceration on his lower limbs. There were no other associated symptoms. A clinical diagnosis of cryoglobulinaemia was considered. Vasculitic screen was negative.
Samples were tested for the presence of cryoglobulins using standard laboratory procedures comparing plasma and serum samples kept at 37°C, with those then cooled and incubated at 4°C to demonstrate cryoprecipitation. Initial examination showed no visible …
Footnotes
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Contributors All authors have contributed to the management of this patient and in writing the manuscript.
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Competing interests None.
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Patient consent Obtained.
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Provenance and peer review Not commissioned; internally peer reviewed.