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Polypectomy and advanced endoscopic resection
  1. Kesavan Kandiah,
  2. Sharmila Subramaniam,
  3. Pradeep Bhandari
  1. Department of Gastroenterology, Queen Alexandra Hospital, Portsmouth, UK
  1. Correspondence to Professor Pradeep Bhandari, Department of Gastroenterology, Queen Alexandra Hospital, Southwick Hill Road, Portsmouth PO6 3LY, UK; pradeep.bhandari{at}


Most colorectal cancers evolve from colorectal adenomatous polyps in a pathway known as the adenoma to carcinoma sequence. Early detection and removal of colorectal adenomas can prevent the development of colorectal cancer. The vast majority of these polyps can be resected endoscopically. Advances in endoscopic resection techniques have led to expanded indications for endoscopic polypectomy, whereby giant polyps, scarred lesions and early cancers may be cured. We will outline conventional endoscopic mucosal resection techniques as well as more complex resection methods such as endoscopic submucosal dissection, full thickness resection and the use of combined endoscopic and laparoscopic assisted approaches to resection. We will also explore the role of a virtual multidisciplinary team to aid decision-making when managing large and complex colorectal polyps. This review will provide an update on the endoscopic management of colorectal polyps and highlight exciting new developments in this ever-expanding field.


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  • Contributors KK wrote the article and performed the literature review; SS performed the literature review and edited the article; PB structured, edited the article and is the corresponding author.

  • Competing interests None.

  • Provenance and peer review Commissioned; externally peer reviewed.