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Review
Recent advances in the diagnosis and management of pancreatic neuroendocrine tumours
  1. Andrew D Hopper1,
  2. Mustafa Jalal1,
  3. Alia Munir2
  4. on behalf of Sheffield Teaching Hospitals European Neuroendocrine Tumour Centre
  1. 1Department of Gastroenterology, Royal Hallamshire Hospital, Sheffield, UK
  2. 2Department of Endocrinology, Royal Hallamshire Hospital, Sheffield, UK
  1. Correspondence to Dr Andrew D Hopper, Department of Gastroenterology, Royal Hallamshire Hospital, Sheffield S10 2JF, UK; andydhopper{at}aol.com

Abstract

The incidence of pancreatic neuroendocrine tumours (PNET) is rising mainly due to the increased use of cross-sectional imaging. Although many PNETs are asymptomatic and non-functioning, the overall 5-year survival is still less than 50%. In this article, we review the advances in diagnosis, classification and staging of PNET that have evolved with the development of new cross-sectional imaging methods and biopsy techniques. With accurate classification, evidence-based, individualised prognostic outcomes and treatments are able to be given which are also discussed.

  • pancreatic cancer
  • pancreatic disorders
  • pancreatic tumours
  • pancreatic islet cell
  • pancreatic endocrine tumour

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Footnotes

  • Contributors ADH designed and drafted the original manuscript. MJ and AM reviewed and updated subsequent and final drafts for important intellectual content of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Not required.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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