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Infliximab in acute severe colitis: getting the right dose
Abstract
Acute severe colitis is a medical emergency and requires prompt treatment with intravenous steroids. Infliximab is typically used as rescue therapy in those who fail to respond to corticosteroids. This article outlines the altered pharmacokinetics of infliximab in acute severe UC and summarised the latest published data surrounding accelerated infliximab dosing.
- infliximab
- ulcerative colitis
- clinical decision making
- inflammatory bowel disease