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A 47-year-old man, with no medical history, presented with a 1-year history of a recurrent skin eruption made of erythematous, erosive, crusty and pruritic plaques involving the scrotum, inguinal and intergluteal skinfolds, trunk and legs (figure 1). Mucosal examination showed glossitis and perleche. He had received topical and systemic antifungal agents without improvement. General examination was normal except a weight loss of 9 kg, without other digestive symptoms and despite a balanced diet. Blood routine tests were normal except a mild normocytic anaemia (11 g/dL) and a hypoalbuminaemia (31 g/L). Nutritional assessment revealed a zinc deficiency (7.37 µmol/L, normal value >12.5 µmol/L). Histological examination of a …
Contributors Submitting author is EA. Corresponding author is SI-H-O. EA and SI-H-O contributed to the conception of the work, collected data and drafted the work. SL, TB, JD, BP, LDM and ES contributed equally to the design of the work, critically reviewed the article. All authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.