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Anal lesions in a 50-year-old HIV-positive man
  1. Johan Chanal1,2,
  2. Nicolas Boo1,
  3. Pierre Sohier3,
  4. Nicolas Dupin1,2
  1. 1 Centre de Santé Sexuelle Paris Cité, Paris, France
  2. 2 CNR IST Bactériennes–Expertise Syphilis, Hôpital Cochin, Paris, France
  3. 3 Department of Pathology, Centre-Université Paris Cité, Paris, France
  1. Correspondence to Dr Johan Chanal, Centre de Santé Sexuelle Paris Cité 75004, Paris, France; johan.chanal{at}

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A man in his 50s presented with painful lesions located on the anal margin. He was HIV positive since 1996. He was treated by a regimen of bictegravir, emtricitabine, tenofovir and alafenamide. The CD4+ lymphocyte count was more than 500 per x10ˆ9/L millimetre with a negative HIV viral load. He had been treated for low-grade human papillomavirus (HPV)-related lesions of the anus in 2018 and was subsequently lost to follow-up. Examination showed cauliflower-like lesions associated with some painful erosions (figure 1A). Anoscopy was normal. …

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  • Contributors Project design/conception: JC and NB. Data and figure chart extraction: PS. Manuscript drafting: JC. Pathology slide images and interpretation: PS. Critical revision of the manuscript: JC, NB, PS and ND. All authors were involved in care of the patient and approved the final draft submitted.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.