RT Journal Article SR Electronic T1 Reversal of intestinal failure-associated liver disease (IFALD): emphasis on its multifactorial nature JF Frontline Gastroenterology JO Frontline Gastroenterol FD BMJ Publishing Group Ltd SP 114 OP 117 DO 10.1136/flgastro-2015-100560 VO 7 IS 2 A1 Christian Hvas A1 Kamelia Kodjabashia A1 Emma Nixon A1 Stephen Hayes A1 Kirstine Farrer A1 Arun Abraham A1 Simon Lal YR 2016 UL http://fg.bmj.com/content/7/2/114.abstract AB Patients with intestinal failure (IF) and home parenteral nutrition commonly develop abnormal liver function tests. The presentations of IF-associated liver disease (IFALD) range from mild cholestasis or steatosis to cirrhosis and decompensated liver disease. We describe the reversal of IFALD in an adult patient with IF secondary to severe Crohn's disease and multiple small bowel resections. The patient developed liver dysfunction and pathology consistent with IFALD. Multiple causal factors were implicated, including nutrition-related factors, catheter sepsis and the use of hepatotoxic medications. Multidisciplinary treatment in a tertiary IF referral centre included aggressive sepsis management, discontinuation of hepatotoxic medications and a reduction of parenteral nutrition dependency through optimisation of enteral nutrition via distal enteral tube feeding. Upon this, liver function tests normalised.