@article {Warnerflgastro-2016-100738, author = {Ben Warner and Emma Johnston and Monica Arenas-Hernandez and Anthony Marinaki and Peter Irving and Jeremy Sanderson}, title = {A practical guide to thiopurine prescribing and monitoring in IBD}, elocation-id = {flgastro-2016-100738}, year = {2016}, doi = {10.1136/flgastro-2016-100738}, publisher = {British Medical Journal Publishing Group}, abstract = {Thiopurines are often the mainstay of treatment for many patients with inflammatory bowel disease. As such, a general understanding of the evidence behind their use and of their metabolism is extremely useful in clinical practice. This review gives a practical overview of thiopurine metabolism, the importance of thiopurine S-methyltransferase testing prior to the start of therapy and the monitoring of thioguanine nucleotide levels while on treatment, guiding a personalised approach to optimising thiopurine therapy.}, issn = {2041-4137}, URL = {https://fg.bmj.com/content/early/2016/08/29/flgastro-2016-100738}, eprint = {https://fg.bmj.com/content/early/2016/08/29/flgastro-2016-100738.full.pdf}, journal = {Frontline Gastroenterology} }