@article {Wilburn68, author = {Jeanette Wilburn and James Twiss and Karen Kemp and Stephen P McKenna}, title = {A qualitative study of the impact of Crohn{\textquoteright}s disease from a patient{\textquoteright}s perspective}, volume = {8}, number = {1}, pages = {68--73}, year = {2017}, doi = {10.1136/flgastro-2015-100678}, publisher = {British Medical Journal Publishing Group}, abstract = {Objective To understand how the lives of people with Crohn{\textquoteright}s disease (CD) are affected. Most research in CD has focused on symptoms and functioning rather than on how these outcomes influence quality of life (QoL).Design As part of a study to develop a CD-specific patient-reported outcome measure, qualitative interviews were conducted with patients from Manchester Royal Infirmary to determine how CD affects QoL. The needs-based model was adopted for the study. The interviews, which took the form of focused conversations covering all aspects of the impact of CD and its treatment, were audio-recorded. Theoretical thematic analysis of the transcripts identified needs affected by CD.Results Thirty patients (60\% female) aged 25{\textendash}68 years were interviewed. Participants had experienced CD for between 2 and 40 years. Nearly 1300 statements relating to the impact of CD were identified. Thirteen main need themes were identified: nutrition, hygiene, continence, freedom from infection, security, self-esteem, role, attractiveness, relationships, intimacy, clear-mindedness, pleasure and autonomy.Conclusions The findings from the interviews indicate that CD has a major impact on need-fulfilment. Such issues should be addressed in CD audit, clinical trials and when evaluating clinical practice.}, issn = {2041-4137}, URL = {https://fg.bmj.com/content/8/1/68}, eprint = {https://fg.bmj.com/content/8/1/68.full.pdf}, journal = {Frontline Gastroenterology} }