PT - JOURNAL ARTICLE AU - Matthew J Brookes AU - Simon Whitehead AU - Daniel R Gaya AU - Antony Barney Hawthorne TI - Practical guidance on the use of faecal calprotectin AID - 10.1136/flgastro-2016-100762 DP - 2018 Apr 01 TA - Frontline Gastroenterology PG - 87--91 VI - 9 IP - 2 4099 - http://fg.bmj.com/content/9/2/87.short 4100 - http://fg.bmj.com/content/9/2/87.full SO - Frontline Gastroenterol2018 Apr 01; 9 AB - Differentiation between inflammatory bowel disease (IBD) and functional gut disorders, and the determination of mucosal disease activity in established cases of IBD remain the cornerstones of disease diagnosis and management. Non-invasive, accurate biomarkers of gut inflammation are needed due to the variability of symptoms, the inaccuracies of currently available blood markers and the cost and invasive nature of endoscopy. Numerous biomarkers have been used and/or considered with some in current use. This article reviews the current evidence base around the indications for using biomarkers and their limitations, with a particular focus on faecal calprotectin.