PT  - JOURNAL ARTICLE
AU  - Foong Way David Tai
AU  - Nicholas Wray
AU  - Reena Sidhu
AU  - Andrew Hopper
AU  - Mark McAlindon
TI  - Factors associated with oesophagogastric cancers missed by gastroscopy: a case–control study
AID  - 10.1136/flgastro-2019-101217
DP  - 2020 May 01
TA  - Frontline Gastroenterology
PG  - 194--201
VI  - 11
IP  - 3
4099  - http://fg.bmj.com/content/11/3/194.short
4100  - http://fg.bmj.com/content/11/3/194.full
SO  - Frontline Gastroenterol2020 May 01; 11
AB  - Introduction There is increasing demand for gastroscopy in the United Kingdom. In around 10% of patients, gastroscopy is presumed to have missed oesophagogastric (OG) cancer prior to diagnosis. We examine patient, endoscopist and service level factors that may affect rates of missed OG cancers.Methods Gastroscopies presumed to have missed OG cancers performed up to 3 years prior to diagnosis were identified over 6 years in Sheffield, UK. Factors related to the patient, endoscopist and endoscopy lists were examined in a case–control study. Procedures which missed cancer were compared with two procedure controls: the procedures which subsequently diagnosed cancer in the same patient, and second, endoscopist matched procedures diagnostic of small benign focal lesions.Results We identified 48 (7.7%) cases of missed OG cancer. Endoscopy lists on which OG cancer diagnoses were missed contained a greater number of total procedures compared with lists on which diagnoses were subsequently made (OR 1.42 95% CI 1.13 to 1.78) and when compared with lists during which matched endoscopists diagnosed benign small focal lesions (OR 1.25, 95% CI 1.02 to 1.52). The use of sedation, endoscopist profession and experience, or time of procedure were not associated with a missed cancer.Conclusion 7.7% of patients diagnosed with OG cancer could have been diagnosed and treated earlier. Our study suggests that endoscopy lists with greater numbers of procedures may be associated with missed OG cancers. The use of sedation, endoscopist background or time of procedure did not increase the risk of missed cancer procedures.