RT Journal Article SR Electronic T1 Recent advances in liver transplantation JF Frontline Gastroenterology JO Frontline Gastroenterol FD BMJ Publishing Group Ltd SP 57 OP 63 DO 10.1136/flgastro-2020-101425 VO 13 IS 1 A1 N Thomas Burke A1 James B Maurice A1 David Nasralla A1 Jonathan Potts A1 Rachel Westbrook YR 2022 UL http://fg.bmj.com/content/13/1/57.abstract AB Liver transplant is a life-saving treatment with 1-year and 5-year survival rates of 90% and 70%, respectively. However, organ demand continues to exceed supply, such that many patients will die waiting for an available organ. This article reviews for the general gastroenterologist the latest developments in the field to reduce waiting list mortality and maximise utilisation of available organs. The main areas covered include legislative changes in organ donation and the new ‘opt-out’ systems being rolled out in the UK, normothermic machine perfusion to optimise marginal grafts, a new national allocation system to maximise benefit from each organ and developments in patient ‘prehabilitation’ before listing. Current areas of research interest, such as immunosuppression withdrawal, are also summarised.