Ref | Symptom | Prevalence of LPR symptoms | p Value | |
CIP (+ve), % | CIP (-ve), % | |||
Chong et al 31 | Overall LPR symptoms | 73.1 | 25.9 | <0.001 |
Chronic cough | 29.2 | 10.6 | <0.01 | |
Sore throat/hoarseness | 54.2 | 11.7 | <0.01 | |
Globus | 23.1 | 7.1 | <0.01 | |
Regurgitation | 42.3 | 13.1 | <0.01 | |
Heartburn | 50.0 | 22.5 | <0.01 | |
Akbayir et al 27 | Upper oesophageal and laryngopharyngeal symptoms | 45 | 21.5 | 0.07 |
Baudet et al 24 | Dysphagia | 21 | 4.0 | <0.001 |
Poyrazoglu et al 32 | Dysphagia | 39.4 | 0 | <0.05 |
Alagozlu et al 20 | Globus | 78.6 | 0 | <0.05 |
Dyspepsia | 88.2 | 97.8 | NS | |
Neumann et al 30 | Dysphagia/odynophagia | 20.8 | 16.4 | <0.001 |
Upper respiratory symptoms | 2.5 | 0.9 | <0.001 | |
Globus | 1.6 | 0.3 | <0.001 | |
Weickert et al 29 | Recurrent hoarseness | 9.1 | 5.6 | 0.5 |
Dysphagia (any grade upper and lower) | 15.2 | 9.4 | NS | |
Heartburn (any grade upper and lower) | 15.2 | 9.4 | NS |
CIP, cervical inlet patch; LPR, laryngopharyngeal reflux.