Comparator | YFCCP | Single FC ≥50 µg/g | Incremental | NNT |
YFCCP as single test FC cut-off ≥50 µg/g | ||||
Total costs (£) | 311 159 | 471 158 | −159 999 | |
Correctly diagnosed IBS cases | 845 | 557 | 289 | |
Correctly diagnosed IBD cases | 76 | 76 | 0 | |
Unnecessary colonoscopies | 74 | 362 | −289 | 3.5 |
Outpatient appointments | 218 | 485 | −267 | 3.7 |
Tibble et al 19 | ||||
Total costs (£) | 311 159 | 368 298 | −50 140 | |
Correctly diagnosed IBS cases | 845 | 735 | 110 | |
Correctly diagnosed IBD cases | 76 | 73 | 3 | |
Unnecessary colonoscopies | 74 | 184 | −110 | 9.1 |
Outpatient appointments | 218 | 320 | −102 | 9.8 |
Waugh et al 3 | ||||
Total costs (£) | 311 159 | 293 290 | 17 869 | |
Correctly diagnosed IBS cases | 845 | 864 | −18 | |
Correctly diagnosed IBD cases | 76 | 75 | 0 | |
Unnecessary colonoscopies | 74 | 55 | 18 | −54.4 |
Outpatient appointments | 218 | 201 | −16 | −58.8 |
IBD, inflammatory bowel disease; IBS, irritable bowel syndrome; NNT, numbers needed to treat; YFCCP, York Faecal Calprotectin Care Pathway.