Table 2

Drugs used in IBD ant their hepatic complications

Hepatic injuryDrug
Drug-induced hepatitisAzathiopirine/6-MP
Methotrexate
5-Amino salyclic acid
Cyclosporine
Anti-TNF
Anti-integrins
Drug-induced cholestasisAzathioprine/6-MP
Anti-TNF
Fibrosis/cirrhosisMethotrexate
Reactivation of HBVAnti TNF therapy
Steroids
Granuloma formationSulfasalazine
SOSAzathiopirine/6-MP
NRHAzathiopirine/6-MP
Peliosis hepatisAzathiopirine/6-MP
SteatohepatitisMethotrexate
Steroids
Parenteral nutrition
  • IBD,¬†inflammatory bowel disease; 6-MP, 6-mercaptopurine; NRH,¬†nodular regenerative hyperplasia; SOS,¬†sinusoidal obstruction syndrome; TNF, tumour necrosis factor.