Summary of adult elective first ever registrations for a liver only transplant: 1 January 2006–31 December 2017
| Variables | SWLU | KCH (Ex. SWLU) | National (Ex. KCH and SWLU) | SWLU versus KCH (P value)* (Ex. SWLU) | SWLU versus national (P value)* (Ex. KCH and SWLU) | |
| Patients (n) | 215 | 1614 | 6662 | |||
| Sex | Male | 149 (69%) | 1071 (66%) | 4375 (66%) | 0.4 | 0.3 |
| Female | 66 (31%) | 543 (34%) | 2287 (34%) | |||
| Ethnicity | White | 208 (97%) | 1386 (86%) | 5909 (89%) | <0.0001 | <0.0001 |
| Non-white | 7 (3%) | 228 (14%) | 753 (11%) | |||
| Indication | Cancers | 18 (8%) | 116 (7%) | 493 (7%) | 0.4 | 0.7 |
| HCV | 34 (16%) | 228 (14%) | 944 (14%) | |||
| ALD | 73 (34%) | 426 (26%) | 2003 (30%) | |||
| HBV | 6 (3%) | 73 (5%) | 179 (3%) | |||
| PSC | 17 (8%) | 140 (9%) | 668 (10%) | |||
| PBC | 13 (6%) | 125 (8%) | 607 (9%) | |||
| AID | 19 (9%) | 180 (11%) | 565 (9%) | |||
| Metabolic | 21 (10%) | 176 (11%) | 779 (12%) | |||
| Other | 14 (6%) | 148 (9%) | 402 (6%) | |||
| ALF | 0 (0%) | 2 (0%) | 22 (0%) | |||
| Blood group | O | 94 (43%) | 736 (46%) | 3068 (46%) | 0.4 | 0.3 |
| A | 81 (38%) | 614 (38%) | 2593 (39%) | |||
| B | 27 (13%) | 204 (13%) | 752 (11%) | |||
| AB | 13 (6%) | 60 (4%) | 249 (4%) | |||
| Outcome at 26 November 2018 | Transplanted | 172 (80%) | 1225 (76%) | 5070 (76%) | 0.5 | 0.4 |
| Died on list | 19 (9%) | 171 (11%) | 585 (9%) | |||
| Removed | 23 (11%) | 197 (12%) | 949 (14%) | |||
| Still active | 1 (0%) | 21 (1%) | 58 (1%) | |||
| Median (IQR) | Age (years) | 57 (49–61) | 54 (45–60) | 55 (47–61) | 0.002 | 0.13 |
| BMI (kg/m2) | 27.1 (24.4–30.2) | 26.4 (23.1–30.0) | 26.9 (23.7–30.9) | 0.02 | 0.6 | |
| Serum Na+ (mmol/L) | 137 (134–140) | 136 (133–139) | 137 (134–140) | 0.02 | 0.7 | |
| Serum Cr (μmol/L) | 74.5 (62–91) | 75 (61–92) | 76 (62–95) | 0.8 | 0.5 | |
| Serum Bili (μmol/L) | 42 (23–80) | 43 (23–83) | 44 (24–87) | 0.7 | 0.4 | |
| INR | 1.4 (1.2–1.6) | 1.3 (1.2–1.6) | 1.3 (1.2–1.6) | 0.7 | 0.5 | |
Bold text indicates significant results.
*Fishers exact or χ2 p values for categorical data and Kruskal-Wallis p values for continuous data (p<0.05 considered statistically significant).
AID, autoimmune disease; ALD, alcoholic liver disease; ALF, acute liver failure; Bili, bilirubin; Cr, creatinine; Ex., excluded; HBV, hepatitis B virus; HCV, hepatitis C virus; KCH, King’s College Hospital; Na+, sodium; PBC, primary biliary cirrhosis; PSC, primary sclerosing cholangitis; SWLU, South West Liver Unit.