Clinical demographics of patients fulfilling the TWW criteria, NG12 and DG30 and characteristics of the CRC identified and missed grouped by criteria; TWW (all comers), NG12 and DG30
| TWW (N=612) | NG12 (N=519) | DG30 (N=79) | |
| Age (mean) | 66.4 | 68.6 | 56.1 |
| Sex | |||
| Male | 300 | 254 | 38 |
| Female | 312 | 265 | 41 |
| Symptoms | |||
| Rectal bleeding | 244 | 230 | 0 |
| Abdominal pain | 175 | 158 | 19 |
| Change in bowel habit | 390 | 349 | 40 |
| Weight loss | 91 | 84 | 7 |
| Anaemia, including iron deficiency | 117 | 94 | 25 |
| Abdominal/rectal mass | 10 | 10 | 0 |
| Family history of CRC | 119 | 104 | 12 |
| FIT median (IQR); µg Hb/g faeces | 1.89 (1–7.48) | 1.9 (1–8.3) | 1.6 (0.9–2.6) |
| Patients with cancer (N=38) | TWW (N=38) | NG12 (N=33) | DG30 (N=5) |
| Symptoms | |||
| Rectal bleeding | 18 | 18 | 0 |
| Abdominal pain | 17 | 13 | 4 |
| Change in bowel habit | 23 | 23 | 0 |
| Weight loss | 8 | 8 | 0 |
| Anaemia, including iron deficiency | 6 | 3 | 3 |
| Abdominal/rectal mass | 10 | 10 | 0 |
| Family history of CRC | 4 | 4 | 0 |
| Median FIT (IQR); µg Hb/g faeces | 261.5 (104.4–910) | 256.9 (100.55–906.33) | 266.1 (199.25–633.5) |
| Missed CRC; FIT negative (N=5) | TWW (N=5) | NG12 (N=5) | DG30 (N=0) |
| Site R/L | 2/3 | 2/3 | 0 |
| Anaemia (%) | 3 (60%) | 3 (60%) | 0 |
| Mass | 2 (40%) | 2 (40%) | 0 |
| Weight loss | 4 (80%) | 4 (80%) | 0 |
| Median FIT (IQR); µg Hb/g faeces | 2.5 (1.1–5.7) | 2.5 (1.1–5.7) | N/A |
CRC, colorectal cancer; FIT, faecal immunochemical test; Hb, haemoglobin; TWW, 2-weeks wait.