Absolute and relative contra-indications to LT
| Absolute contraindications | Relative contraindications* |
| Untreated HIV* | Inadequate social support |
| Severe extrahepatic disease with predicted mortality >50% at 5 years including psychiatric disorder | Smoking |
| Severe irreversible pulmonary disease | Certain anatomical variants |
| Ongoing alcohol misuse | Extensive previous abdominal surgery |
| Active illicit drug use | BMI >40 kg/m2 |
| Certain anatomic variants | Poor clinic attendance and/or adherence |
| Ongoing extra-hepatic sepsis* | |
| Active or previous extra-hepatic malignancy† | |
| Liver cancer outside criteria* |
*These contra-indications can be temporary and require discussion with LTU.
†LT is considered for patients with neuroendocrine tumours (requires referral to national panel).46
BMI, body mass index; LT, liver transplant; LTU, liver transplant unit.