Table 1

Nice recommended tofacitinib dosing regimen for patients with moderately to severely active UC1

Anti-TNF naïve dosingPrevious anti-TNF exposure dosing
Induction (8 weeks)10 mg bd10 mg bd
Maintenance5 mg bd10 mg bd
Loss of responseIncrease to 10 mg bd–

  • bd, two times per day; TNF, tumour necrosis factor.