Table 8

Selected physiological changes following RYGB and VSG that are implicated in weight loss and improvements in postprandial glucose metabolism. Adapted from19

RYGBVSG
Glucagon-like peptide-1↑↑
Peptide YY 3–36↑↑
Ghrelin↓↓
Glucose-dependent insulinotropic polypeptide
Oxyntomodulin
Neurotensin
Bile acids
Gut microbiota composition‘Lean’ phenotype
Vagal afferent signalling
  • RYGB, Roux-en-Y gastric bypass; VSG, vertical sleeve gastrectomy.