Baseline characteristics of the study subjects
| Total (n=180) | Mild Fibrosis (n=61) | Moderate- Severe fibrosis (n=119) | p-value | |
|---|---|---|---|---|
| Age (years) | 2.4 (0.7 – 4.9) | 3.8 (1.59 -6.45) | 1.5 (0.66—3.8) | 0.001 |
| Male | 61% | 60.5% | 67% | 0.38 |
| Bilirubin | 27 (8 -203) | 10 (5 -75) | 81 (12 -216) | <0.001 |
| ALT | 87 (37 - 206) | 51 (27- 142) | 118 (48 -219) | 0.002 |
| AST | 120 (47 -373) | 59 (35- 156) | 157 (60 -405) | <0.001 |
| GGT | 75 (33 – 131) | 46 (20–142) | 85 (49 -129) | 0.023 |
| ALP | 641 (371 - 995) | 599 (344 -844) | 644 (416 – 1052) | 0.215 |
| Albumin | 35 (31- 40) | 35 (29 -41) | 35 (31- 39) | 0.998 |
| Prothrombin time | 12 (12 - 13) | 12 (11 - 13) | 12 (12- 14) | NS |
| Platelets | 168 (106 -250) | 206 (134- 292) | 155 (93 – 227) | 0.001 |
| APRI | 1.72 (0.62 -6.05) | 0.79 (0.32 -2.4) | 2.56 (0.77 -10.3) | <0.001 |
| FIB4 | 0.17 (0.09– 0.38) | 0.12 (0.06 -0.38) | 0.19 (0.11 -0.38) | 0.091 |
| AST/ALT | 1.4 (1.15- 1.99) | 1.35 (1.07 -1.75) | 1.54 (1.2- 2.11) | 0.006 |