Presence of clinically significant findings at upper GI endoscopy in patients with and without symptoms compatible with FD, stratified according to the presence or absence of alarm features
| Symptoms compatible with FD (n=221) | |||
| No alarm features present (n=35) | Alarm features present (n=186) | P value | |
| Upper GI cancer | 0 (0%) | 3 (1.6%) | 0.60 |
| Barrett’s oesophagus | 0 (0%) | 7 (4%) | 0.29 |
| Grade C/D oesophagitis | 0 (0%) | 2 (1%) | 0.71 |
| Strictures | 0 (0%) | 4 (2%) | 0.50 |
| Peptic ulcer disease | 0 (0%) | 5 (3%) | 0.42 |
| Any of the above | 0 (0%) | 20 (11%) | 0.03 |
| Symptoms not compatible with FD (n=166) | |||
| No alarm features present (n=29) | Alarm features present (n=137) | P value | |
| Upper GI cancer | 0 (0%) | 2 (1.5%) | 0.68 |
| Barretts oesophagus | 0 (0%) | 8 (6%) | 0.21 |
| Grade C/D oesophagitis | 0 (0%) | 1 (0.7%) | 0.83 |
| Strictures | 0 (0%) | 3 (2%) | 0.56 |
| Peptic ulcer disease | 2 (7%) | 2 (1.5%) | 0.14 |
| Any of the above | 2 (7%) | 15 (11%) | 0.40 |
FD, functional dyspepsia; GI, gastrointestinal.