Stent-induced pancreatic ductal and parenchymal changes: correlation of endoscopic ultrasound with ERCP☆,☆☆,★
Section snippets
MATERIALS AND METHODS
The subjects of this study were 25 patients who underwent short-term pancreatic duct stenting (mean time, 22 days; range, 8 to 60 days) and had an endoscopic ultrasound (EUS) evaluation of the pancreas at the time of stent removal (Table 1). The pancreatic stents were placed for guiding a pancreatic sphincterotomy (n = 9); treatment of pancreas divisum (n = 6); guiding a pre-cut biliary endoscopic sphincterotomy (n = 6); pancreatic protection following standard biliary endoscopic sphincterotomy
RESULTS
Twenty-one patients had a normal baseline pancreatogram, whereas 4 had changes of mild chronic pancreatitis (Table 1). Of the 16 evaluated by ERCP at stent removal, 9 (56.3%) had one or more new ductographic changes (Fig. 1, Fig. 2; Table 2).
DISCUSSION
Polyethylene pancreatic duct stents are being utilized for the treatment of a variety of benign pancreatic disorders.12 Although therapeutic benefit has been reported for pancreatic stenting, it has been evident that morphologic changes of the pancreatic duct directly related to this therapy occur in the majority of patients. In summarizing the results of seven published series, new ductal changes were seen in 54% of 297 patients stented (Table 4). Preliminary data suggested that these
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Cited by (0)
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From the Department of Medicine, Division of Gastroenterology/Hepatology, Indiana University School of Medicine, Indiana University Medical Center, Indianapolis, Indiana.
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Reprint requests: Stuart Sherman, MD, Gastroenterology, Indiana University Hospital, 550 North University Blvd., Suite 2300, Indianapolis, IN 46202-5000.
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