Gastroesophageal reflux disease treatment: side effects and complications of fundoplication

Clin Gastroenterol Hepatol. 2013 May;11(5):465-71; quiz e39. doi: 10.1016/j.cgh.2012.12.006. Epub 2012 Dec 23.

Abstract

Even skilled surgeons will have complications after antireflux surgery. Fortunately, the mortality is low (<1%) with laparoscopic surgery, immediate postoperative morbidity is uncommon (5%-20%), and conversion to an open operation is <2.5%. Common late postoperative complications include gas-bloat syndrome (up to 85%), dysphagia (10%-50%), diarrhea (18%-33%), and recurrent heartburn (10%-62%). Most of these complications improve during the 3-6 months after surgery. Dietary modifications, pharmacologic therapies, and esophageal dilation may be helpful. Failures after antireflux surgery usually occur within the first 2 years after the initial operation. They fall into 5 patterns: herniation of the fundoplication into the chest, slipped fundoplication, tight fundoplication, paraesophageal hernia, and malposition of the fundoplication. Reoperation rates range from 0%-15% and should be performed by experienced foregut surgeons.

Publication types

  • Review

MeSH terms

  • Deglutition Disorders / epidemiology
  • Deglutition Disorders / etiology
  • Diarrhea / epidemiology
  • Diarrhea / etiology
  • Diet / methods
  • Dilatation
  • Fundoplication / adverse effects*
  • Gastroesophageal Reflux / surgery*
  • Gastrointestinal Agents / administration & dosage
  • Heartburn / epidemiology
  • Heartburn / etiology
  • Humans
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / pathology*

Substances

  • Gastrointestinal Agents