Third European evidence-based consensus on diagnosis and management of ulcerative colitis. Part 1: definitions, diagnosis, extra-intestinal manifestations …
F Magro, P Gionchetti, R Eliakim… - Journal of Crohn's …, 2017 - academic.oup.com
1.2. Definitions Ulcerative colitis [UC] is a chronic inflammatory condition that causes
continuous mucosal inflammation of the colon, usually without granulomas on biopsy. It …
continuous mucosal inflammation of the colon, usually without granulomas on biopsy. It …
[HTML][HTML] Tight junctions in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer
J Landy, E Ronde, N English, SK Clark… - World journal of …, 2016 - ncbi.nlm.nih.gov
Inflammatory bowel diseases are characterised by inflammation that compromises the
integrity of the epithelial barrier. The intestinal epithelium is not only a static barrier but has …
integrity of the epithelial barrier. The intestinal epithelium is not only a static barrier but has …
Forty-year analysis of colonoscopic surveillance program for neoplasia in ulcerative colitis: an updated overview
Objectives: This study provides an overview of the largest and longest-running colonoscopic
surveillance program for colorectal cancer (CRC) in patients with long-standing ulcerative …
surveillance program for colorectal cancer (CRC) in patients with long-standing ulcerative …
Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study
Background Anti-TNF drugs are effective treatments for the management of Crohn's disease
but treatment failure is common. We aimed to identify clinical and pharmacokinetic factors …
but treatment failure is common. We aimed to identify clinical and pharmacokinetic factors …
Characteristics of intestinal dendritic cells in inflammatory bowel diseases
Background & Aims: Dendritic cells (DCs) recognize and respond to microbial structures
using pattern recognition receptors, including Toll-like receptors (TLRs). In the intestine, DCs …
using pattern recognition receptors, including Toll-like receptors (TLRs). In the intestine, DCs …
[HTML][HTML] COVID-19 vaccine-induced antibody responses in immunosuppressed patients with inflammatory bowel disease (VIP): a multicentre, prospective, case …
JL Alexander, NA Kennedy, H Ibraheim… - The lancet …, 2022 - thelancet.com
Background The effects that therapies for inflammatory bowel disease (IBD) have on
immune responses to SARS-CoV-2 vaccination are not yet fully known. Therefore, we …
immune responses to SARS-CoV-2 vaccination are not yet fully known. Therefore, we …
Randomised, double-blind, placebo-controlled trial of fructo-oligosaccharides in active Crohn's disease
Introduction The commensal intestinal microbiota drive the inflammation associated with
Crohn's disease. However, bacteria such as bifidobacteria and Faecalibacterium prausnitzii …
Crohn's disease. However, bacteria such as bifidobacteria and Faecalibacterium prausnitzii …
The use of faecal microbiota transplant as treatment for recurrent or refractory Clostridium difficile infection and other potential indications: joint British Society of …
Interest in the therapeutic potential of faecal microbiota transplant (FMT) has been
increasing globally in recent years, particularly as a result of randomised studies in which it …
increasing globally in recent years, particularly as a result of randomised studies in which it …
Smokers with active Crohn's disease have a clinically relevant dysbiosis of the gastrointestinal microbiota
JL Benjamin, CRH Hedin… - Inflammatory bowel …, 2012 - academic.oup.com
Abstract Background Patients with Crohn's disease (CD) have an intestinal dysbiosis with
components of the microbiota exerting differential immune effects. Smoking is associated …
components of the microbiota exerting differential immune effects. Smoking is associated …
[HTML][HTML] Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with …
S Lin, NA Kennedy, A Saifuddin, DM Sandoval… - Nature …, 2022 - nature.com
Anti tumour necrosis factor (anti-TNF) drugs increase the risk of serious respiratory infection
and impair protective immunity following pneumococcal and influenza vaccination. Here we …
and impair protective immunity following pneumococcal and influenza vaccination. Here we …