Unacceptable failures: the final report of the Lancet Commission into liver disease in the UK

R Williams, G Aithal, GJ Alexander, M Allison… - The Lancet, 2020 - thelancet.com
This final report of the Lancet Commission into liver disease in the UK stresses the
continuing increase in burden of liver disease from excess alcohol consumption and obesity …

[HTML][HTML] Prednisolone or pentoxifylline for alcoholic hepatitis

MR Thursz, P Richardson, M Allison… - … England Journal of …, 2015 - Mass Medical Soc
Background Alcoholic hepatitis is a clinical syndrome characterized by jaundice and liver
impairment that occurs in patients with a history of heavy and prolonged alcohol use. The …

Allogeneic cytotoxic T-cell therapy for EBV-positive posttransplantation lymphoproliferative disease: results of a phase 2 multicenter clinical trial

T Haque, GM Wilkie, MM Jones… - Blood, The Journal …, 2007 - ashpublications.org
We present the results of a multicenter clinical trial using Epstein-Barr virus (EBV)–specific
cytotoxic T lymphocytes (CTLs) generated from EBV-seropositive blood donors to treat …

[HTML][HTML] New dimensions for hospital services and early detection of disease: a review from the Lancet Commission into liver disease in the UK

R Williams, C Alessi, G Alexander, M Allison… - The Lancet, 2021 - thelancet.com
This Review, in addressing the unacceptably high mortality of patients with liver disease
admitted to acute hospitals, reinforces the need for integrated clinical services. The …

Primary prophylaxis of variceal hemorrhage: a randomized controlled trial comparing band ligation, propranolol, and isosorbide mononitrate

HF Lui, AJ Stanley, EH Forrest, R Jalan, WS Hislop… - Gastroenterology, 2002 - Elsevier
Background & Aims: This randomized controlled trial compared variceal band ligation (VBL),
propranolol (PPL), and isosorbide-5-mononitrate (ISMN) in the prevention of first …

High risk of cytomegalovirus infection following solid organ transplantation despite prophylactic therapy

H Harvala, C Stewart, K Muller, S Burns… - Journal of medical …, 2013 - Wiley Online Library
Cytomegalovirus infection (CMV) in solid organ transplant recipients is a major clinical
problem. The aim of this study was to evaluate the incidence of CMV infection and its …

Palliative care for people with advanced liver disease: a feasibility trial of a supportive care liver nurse specialist

B Kimbell, SA Murray, H Byrne, A Baird… - Palliative …, 2018 - journals.sagepub.com
Background: Liver disease is an increasing cause of death worldwide but palliative care is
largely absent for these patients. Aim: We conducted a feasibility trial of a complex …

Impaired pressor reactivity in cirrhosis: evidence for a peripheral vascular defect

AJ Macgilchrist, D Sumner, JL Reid - Hepatology, 1991 - journals.lww.com
The blood pressure responses to intravenous infusions of norepinephrine and angiotensin
II, sympathetic and nonsympathetic vasoconstricting agents, respectively, were measured in …

The Liverpool alcohol‐related liver disease algorithm identifies twice as many emergency admissions compared to standard methods when applied to Hospital …

A Dhanda, K Bodger, S Hood, C Henn… - Alimentary …, 2023 - Wiley Online Library
Summary Background Emergency admissions in England for alcohol‐related liver disease
(ArLD) have increased steadily for decades. Statistics based on administrative data typically …

Demons in the North Atlantic: Variability of deep ocean ventilation

GA MacGilchrist, HL Johnson, C Lique… - Geophysical …, 2021 - Wiley Online Library
Translation of atmospheric forcing variability into the ocean interior via ocean ventilation is
an important aspect of transient climate change. On a seasonal timescale in the subtropics …