IL‐6 promotes immune responses in human ulcerative colitis and induces a skin‐homing phenotype in the dendritic cells and T cells they stimulate

D Bernardo, S Vallejo‐Díez, ER Mann… - European journal of …, 2012 - Wiley Online Library
Dendritic cells (DC s) control the type and location of immune responses. Ulcerative colitis
(UC) is considered a T h2 disease mediated by IL‐13 where up to one third of patients can …

National prospective cohort study of the burden of acute small bowel obstruction

MJ Lee, AE Sayers, TM Drake, PJ Marriott… - BJS open, 2019 - academic.oup.com
Background Small bowel obstruction is a common surgical emergency, and is associated
with high levels of morbidity and mortality across the world. The literature provides little …

Malnutrition, nutritional interventions and clinical outcomes of patients with acute small bowel obstruction: results from a national, multicentre, prospective audit

MJ Lee, AE Sayers, TM Drake, P Singh, M Bradburn… - BMJ open, 2019 - bmjopen.bmj.com
Objective The aim of this study was to assess the nutritional status of patients presenting
with small bowel obstruction (SBO), along with associated nutritional interventions and …

JAG consensus statements for training and certification in oesophagogastroduodenoscopy

K Siau, ILP Beales, A Haycock, D Alzoubaidi… - Frontline …, 2022 - fg.bmj.com
Introduction Training and quality assurance in oesophagogastroduodenoscopy (OGD) is
important to ensure competent practice. A national evidence-based review was undertaken …

[HTML][HTML] Chemokine (CC motif) receptor 2 mediates dendritic cell recruitment to the human colon but is not responsible for differences observed in dendritic cell …

D Bernardo, L Durant, ER Mann, E Bassity… - Cellular and molecular …, 2016 - Elsevier
Background & Aims Most knowledge about gastrointestinal (GI)-tract dendritic cells (DC)
relies on murine studies where CD103+ DC specialize in generating immune tolerance with …

[HTML][HTML] Impact of a simulation-based induction programme in gastroscopy on trainee outcomes and learning curves

K Siau, J Hodson, P Neville, J Turner… - World journal of …, 2020 - ncbi.nlm.nih.gov
BACKGROUND Pre-clinical simulation-based training (SBT) in endoscopy has been shown
to augment trainee performance in the short-term, but longer-term data are lacking. AIM To …

T-cell proliferation and forkhead box P3 expression in human T cells are dependent on T-cell density: physics of a confined space?

D Bernardo, HO Al-Hassi, ER Mann, CT Tee… - Human immunology, 2012 - Elsevier
T-cell proliferation rates in vitro depend on factors including initial T-cell number, dose of
stimulus, culture time, and available physical space. The role of forkhead box P3 (FoxP3) in …

The hidden burden of community enteral feeding on the emergency department

D Barrett, V Li, S Merrick… - Journal of Parenteral …, 2021 - Wiley Online Library
Background Enteral feeding tubes are associated with their most serious complications in
the days and weeks after insertion, but there are limited published data in the literature on …

JAG consensus statements for training and certification in colonoscopy

K Siau, S Pelitari, S Green, B McKaig… - Frontline …, 2023 - fg.bmj.com
Introduction In the UK, endoscopy certification is awarded when trainees attain minimum
competency standards for independent practice. A national evidence-based review was …

JAG consensus statements for training and certification in flexible sigmoidoscopy

K Siau, S Pelitari, S Green, B McKaig… - Frontline …, 2023 - fg.bmj.com
Introduction Joint Advisory Group (JAG) certification in endoscopy is awarded when trainees
attain minimum competency standards for independent practice. A national evidence-based …