User profiles for "author:Brian D Nicholson"
 | Brian D NicholsonGP and Associate Professor Verified email at phc.ox.ac.uk Cited by 3376 |
[HTML][HTML] At what times during infection is SARS-CoV-2 detectable and no longer detectable using RT-PCR-based tests? A systematic review of individual participant …
Background Tests for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral
ribonucleic acid (RNA) using reverse transcription polymerase chain reaction (RT-PCR) are …
ribonucleic acid (RNA) using reverse transcription polymerase chain reaction (RT-PCR) are …
Blood CEA levels for detecting recurrent colorectal cancer
BD Nicholson, B Shinkins, I Pathiraja… - Cochrane Database …, 2015 - cochranelibrary.com
Background Testing for carcino‐embryonic antigen (CEA) in the blood is a recommended
part of follow‐up to detect recurrence of colorectal cancer following primary curative …
part of follow‐up to detect recurrence of colorectal cancer following primary curative …
[HTML][HTML] Overtesting and undertesting in primary care: a systematic review and meta-analysis
Background Health systems are currently subject to unprecedented financial strains.
Inappropriate test use wastes finite health resources (overuse) and delays diagnoses and …
Inappropriate test use wastes finite health resources (overuse) and delays diagnoses and …
[HTML][HTML] Impact of the COVID-19 pandemic on the detection and management of colorectal cancer in England: a population-based study
EJA Morris, R Goldacre, E Spata, M Mafham… - The lancet …, 2021 - thelancet.com
Background There are concerns that the COVID-19 pandemic has had a negative effect on
cancer care but there is little direct evidence to quantify any effect. This study aims to …
cancer care but there is little direct evidence to quantify any effect. This study aims to …
[HTML][HTML] Multi-cancer early detection test in symptomatic patients referred for cancer investigation in England and Wales (SYMPLIFY): a large-scale, observational …
BD Nicholson, J Oke, PS Virdee, DA Harris… - The Lancet …, 2023 - thelancet.com
Background Analysis of circulating tumour DNA could stratify cancer risk in symptomatic
patients. We aimed to evaluate the performance of a methylation-based multicancer early …
patients. We aimed to evaluate the performance of a methylation-based multicancer early …
Faecal immunochemical testing (FIT) in patients with signs or symptoms of suspected colorectal cancer (CRC): a joint guideline from the Association of Coloproctology …
KJ Monahan, MM Davies, M Abulafi, A Banerjea… - Gut, 2022 - gut.bmj.com
Faecal immunochemical testing (FIT) has a high sensitivity for the detection of colorectal
cancer (CRC). In a symptomatic population FIT may identify those patients who require …
cancer (CRC). In a symptomatic population FIT may identify those patients who require …
[HTML][HTML] Implementation of non-communicable disease policies: a geopolitical analysis of 151 countries
LN Allen, BD Nicholson, BYT Yeung… - The Lancet Global …, 2020 - thelancet.com
Background Most countries have endorsed WHO non-communicable disease (NCD) best
buy policies, but we know very little about global implementation patterns and about the …
buy policies, but we know very little about global implementation patterns and about the …
Association between blood pressure control and coronavirus disease 2019 outcomes in 45 418 symptomatic patients with hypertension: an observational cohort study
Hypertension has been identified as a risk factor for coronavirus disease 2019 (COVID-19)
and associated adverse outcomes. This study examined the association between …
and associated adverse outcomes. This study examined the association between …
Understanding the role of GPs' gut feelings in diagnosing cancer in primary care: a systematic review and meta-analysis of existing evidence
Background Growing evidence for the role of GPs' gut feelings in cancer diagnosis raises
questions about their origin and role in clinical practice. Aim To explore the origins of GPs' …
questions about their origin and role in clinical practice. Aim To explore the origins of GPs' …
Excess mortality in the first COVID pandemic peak: cross-sectional analyses of the impact of age, sex, ethnicity, household size, and long-term conditions in people of …
Background The SARS-CoV-2 pandemic has passed its first peak in Europe. Aim To
describe the mortality in England and its association with SARS-CoV-2 status and other …
describe the mortality in England and its association with SARS-CoV-2 status and other …