Fistulating Crohn's disease (CD) comprises fistulae arising in the perianal area, together
with those communicating between the intestine and other organs or the abdominal wall …

Background & Aims The management of inflammatory bowel disease (IBD) poses a
particular challenge during pregnancy because the health of both the mother and the fetus …

Aliment Pharmacol Ther 2011; 34: 113–124 Summary Background There is no international
agreement on scoring systems used to measure disease activity in ulcerative colitis, nor is …

Background The comparative efficacy and safety of infliximab and azathioprine therapy
alone or in combination for Crohn's disease are unknown. Methods In this randomized …

This paper is the second in a series of two publications relating to the European Crohn's and
Colitis Organisation [ECCO] evidence-based consensus on the diagnosis and management …

Objective The introduction of anti tumour necrosis factor-α (anti-TNFα) therapy might impact
healthcare expenditures, but there are limited data regarding the costs of inflammatory …

Dendritic cells (DC s) and monocyte‐derived macrophages (MΦs) are key components of
intestinal immunity. However, the lack of surface markers differentiating MΦs from DC s has …

GWAS have identified> 200 risk loci for Inflammatory Bowel Disease (IBD). The majority of
disease associations are known to be driven by regulatory variants. To identify the putative …

Background Mouse models have shown that interleukin (IL) 6 stimulates survival,
proliferation and progression to cancer of intestinal epithelial cells via activation of signal …

Background & Aims Patients with perianal fistulizing Crohn's disease have a poor prognosis
because these lesions do not heal well. We evaluated the effects of local administration of …