Metabolomics and lipidomics in NAFLD: biomarkers and non-invasive diagnostic tests

M Masoodi, A Gastaldelli, T Hyötyläinen… - Nature reviews …, 2021 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases
worldwide and is often associated with aspects of metabolic syndrome. Despite its …

[HTML][HTML] Biomarkers and subtypes of deranged lipid metabolism in non-alcoholic fatty liver disease

JM Mato, C Alonso, M Noureddin… - World journal of …, 2019 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is a heterogeneous and complex disease that is
imprecisely diagnosed by liver biopsy. NAFLD covers a spectrum that ranges from simple …

Synthetic approaches for the conjugation of porphyrins and related macrocycles to peptides and proteins

F Giuntini, CMA Alonso, RW Boyle - Photochemical & Photobiological …, 2011 - Springer
The association of photosensitisers to peptides and proteins is a recognised and successful
method for enhancing the selectivity and efficacy of photodynamic treatment. The covalent …

[HTML][HTML] The MLL recombinome of acute leukemias in 2017

C Meyer, T Burmeister, D Gröger, G Tsaur, L Fechina… - Leukemia, 2018 - nature.com
Chromosomal rearrangements of the human MLL/KMT2A gene are associated with infant,
pediatric, adult and therapy-induced acute leukemias. Here we present the data obtained …

Using focus groups in educational research: Exploring teachers' perspectives on educational change

J Gilflores, CG Alonso - Evaluation review, 1995 - journals.sagepub.com
In the past few years, focus group research has been used increasingly in fields different
from market research, in which the technique was developed. The application of focus …

Metabolomic identification of subtypes of nonalcoholic steatohepatitis

C Alonso, D Fernández-Ramos, M Varela-Rey… - Gastroenterology, 2017 - Elsevier
Background & Aims Nonalcoholic fatty liver disease (NAFLD) is a consequence of defects in
diverse metabolic pathways that involve hepatic accumulation of triglycerides. Features of …

Liquid chromatography− mass spectrometry-based parallel metabolic profiling of human and mouse model serum reveals putative biomarkers associated with the …

J Barr, M Vázquez-Chantada, C Alonso… - Journal of proteome …, 2010 - ACS Publications
Nonalcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease in
most western countries. Current NAFLD diagnosis methods (eg, liver biopsy analysis or …

Lineage switch in childhood acute leukemia: an unusual event with poor outcome

JG Rossi, AR Bernasconi, CN Alonso… - American journal of …, 2012 - Wiley Online Library
Although rarely, switches between lymphoid and myeloid lineages may occur during
treatment of acute leukemias (AL). Correct diagnosis relies upon confirmation by …

[HTML][HTML] The PPAR α/γ agonist saroglitazar improves insulin resistance and steatohepatitis in a diet induced animal model of nonalcoholic fatty liver disease

DP Kumar, R Caffrey, J Marioneaux, PK Santhekadur… - Scientific reports, 2020 - nature.com
Insulin resistance and hepatic lipid accumulation constitute the metabolic underpinning of
nonalcoholic steatohepatitis (NASH). We tested the hypothesis that saroglitazar, a PPAR α/γ …

[PDF][PDF] Metabolomic‐based noninvasive serum test to diagnose nonalcoholic steatohepatitis: results from discovery and validation cohorts

R Mayo, J Crespo, I Martínez‐Arranz… - Hepatology …, 2018 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is the most common type of chronic liver disease
worldwide and includes a broad spectrum of histologic phenotypes, ranging from simple …