These updated guidelines on the management of variceal haemorrhage have been
commissioned by the Clinical Services and Standards Committee (CSSC) of the British …

Current therapy for preventing the first variceal bleed includes beta-blocker and variceal
band ligation (VBL). VBL has lower bleeding rates, with no differences in survival, whereas …

Objective Recent data have suggested that non-selective β-blockers (NSBB) are associated
with increased mortality in patients with cirrhosis and refractory ascites. However, other …

The skull bones must grow in a coordinated, three‐dimensional manner to coalesce and
form the head and face. Mammalian skull bones have a dual embryonic origin from cranial …

Background: Although renal dysfunction is a common complication of acute liver failure
(ALF) with significant prognostic implications, the pathophysiological mechanisms remain …

Background & Aims The growing discrepancy between supply and demand for liver
transplantation has necessitated a greater use of higher risk grafts. Donation after …

Abstract Background & Aims In the absence of overt infection, the systemic inflammatory
response is increasingly recognised as a pathogenetic factor in the circulatory dysfunction of …

Smoking is the world's leading cause of premature mortality responsible for an estimated 5
million deaths each year. Although the negative health implications of cigarette smoking in …

Donation after cardiac death liver transplant recipients have an increased frequency of acute
kidney injury (AKI). This suggests that hepatic ischemia‐reperfusion injury may play a critical …

Non-alcoholic fatty liver disease (NAFLD) is the term used to describe the alcohol-like liver
injury that occurs in the absence of alcohol abuse. It embraces a range of histological …