[HTML][HTML] Network biology approaches to achieve precision medicine in inflammatory bowel disease

JP Thomas, D Modos, T Korcsmaros… - Frontiers in …, 2021 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic immune-mediated condition arising due to
complex interactions between multiple genetic and environmental factors. Despite recent …

[HTML][HTML] A systems genomics approach to uncover patient-specific pathogenic pathways and proteins in ulcerative colitis

J Brooks-Warburton, D Modos, P Sudhakar… - Nature …, 2022 - nature.com
We describe a precision medicine workflow, the integrated single nucleotide polymorphism
network platform (iSNP), designed to determine the mechanisms by which SNPs affect …

[HTML][HTML] Analysing MiRNA-target gene networks in inflammatory bowel disease and other complex diseases using transcriptomic data

JP Thomas, M Ölbei, J Brooks-Warburton… - Genes, 2022 - mdpi.com
Patients with inflammatory bowel disease (IBD) are known to have perturbations in
microRNA (miRNA) levels as well as altered miRNA regulation. Although experimental …

Artificial intelligence and inflammatory bowel disease: practicalities and future prospects

J Brooks-Warburton, J Ashton, A Dhar, T Tham… - Frontline …, 2022 - fg.bmj.com
Artificial intelligence (AI) is an emerging technology predicted to have significant
applications in healthcare. This review highlights AI applications that impact the patient …

Perceptions, behaviours and barriers towards exercise practices in inflammatory bowel disease

JK Sinclair, J Brooks-Warburton, L Bottoms - PLOS ONE, 2024 - clok.uclan.ac.uk
Inflammatory bowel disease (IBD), a chronic disease affecting the digestive tract, has a
significant impact on health-related quality of life. Pharmaceutical treatment is typically …

[HTML][HTML] Health Benefits of Montmorency Tart Cherry Juice Supplementation in Adults with Mild to Moderate Ulcerative Colitis: A Protocol for a Placebo Randomized …

J Sinclair, S Dillon, R Allan, J Brooks-Warburton… - Methods and …, 2023 - mdpi.com
Ulcerative colitis, characterized by its relapsing and remissive nature, negatively affects
perception, body image, and overall quality of life. The associated financial burden …

The importance of high-quality 'big data'in the application of artificial intelligence in inflammatory bowel disease

JJ Ashton, J Brooks-Warburton, PB Allen… - Frontline …, 2023 - fg.bmj.com
The rise of artificial intelligence (AI) in healthcare provides an opportunity to improve clinical
care and patient outcomes. Gastroenterology may be seen as a leader in the application of …

[CITATION][C] Sa1795 SYSTEMS GENOMICS AND NETWORK APPROACHES UNCOVER HOW SINGLE NUCLEOTIDE POLYMORPHISMS IN CROHN'S DISEASE …

D Modos, M Poletti, J Brooks-Warburton, B Bohar… - Gastroenterology, 2023 - Elsevier